|
KMID : 1004620130190020298
|
|
Clinical Nursing Research
2013 Volume.19 No. 2 p.298 ~ p.308
|
|
|
The Influences of Depression, Anxiety, Social Support and Knowledge of Anticancer Drugs on the Chemotherapy-induced Peripheral Neuropathy among Colorectal Cancer Patients Receiving Oxaliplatin
|
|
Han Sang-Sook
Han Sang-Soon
Han Jeong-Won
|
|
|
Abstract
|
|
|
Purpose: The purpose of this study was to identify factors influencing chemotherapy-induced peripheral neuropathy among colorectal cancer patients receiving oxaliplatin.
Methods: A total of 132 patients hospitalized for chemotherapy were surveyed at K University Hospital in Seoul, Korea. This study was a descriptive causal relationship study using a self-report questionnaire survey method. Correlation and multiple regression analysis between the factors were performed using SPSS 18.0.
Results: The regression model was significant (F=31.64, p<.001), which meaned that the experience of chemotherapy-induced peripheral neuropathy among the participants was statistically significant. The factors influencing the chemotherapy-induced peripheral neuropathy were depression (β=.34, p<.001), followed by anxiety (β=.32, p<.001), medical staff support (β=-.17, p=.037) and the level of knowledge of anticancer drugs (β=-.16, p=.045). The explanatory power of these factors on the chemotherapy-induced peripheral neuropathy of colorectal cancer patients was 69%.
Conclusion: The factors influencing the chemotherapy-induced peripheral neuropathy of colorectal cancer patients receiving oxaliplatin were identified as depression, anxiety, level of knowledge of anticancer drugs and medical staff support.
|
|
|
KEYWORD
|
|
|
Peripheral nervous system diseases, Depression, Anxiety, Social support, Knowledge
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|